Ovarian hypofunction

Ovarian hypofunction is the reduced function of ovaries cauasing a decrease in production of hormones. Women with ovarian hypofunction may experience symptoms of menopause and makes it difficult for a woman to get pregnant.

Signs and Symptoms:

  • Hot flashes
  • Irregular or absent periods
  • Mood swings
  • Night sweats
  • Vaginal dryness


  • Genetic factors such as chromosome abnormalities
  • Certain autoimmune disorders
  • Chemotherapy
  • Radiation therapy


Doctors use estrogen therapy which provides relief in menstrual symptoms and prevents bone loss. But this therapy does not increase your chance of becoming pregnant. A study shows that 1 in 10 women with ovarian hypofunction will be able to get pregnant. The chance of successfully getting pregnant increases to 50% when using a fertilized donor egg (an egg from another woman).

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